Statistical genetics involves the development and application of statistical methods for interpreting genetic data, and is commonly involved in the study of human genetics.
The statistical genetics group at GOHaD are involved in the design and analysis of genetic data and other large biological data sets from complex human disease studies, incorporating clinical aspects, laboratory issues, and modern statistical analyses. GOHaD statistical geneticists collaborate widely nationally and internationally on studies of heart disease, psychiatric disease, cancer, pregnancy disorders, and health-related behaviours. We have expertise in h [...]Read More
Bioinformatics involves the application of computer science and software tools to understand and solve complex biological problems.
GOHaD staff have skills in storage, analysis and presentation of biological data. Skill sets range from database administration, software engineering, pipeline analysis of (particularly family based) DNA sequence and methylation information. Importantly, this combines with an ability to interpret this data and scientific concepts in-house and with our collaborative partners. This ties in well with the WA DNA BANK (WADB) at GOHaD, where w [...]Read More
Molecular and Functional Genetics
Molecular genetics is the field of biology that studies the structure and function of genes at a molecular level.
The common objective of contemporary common human disease genetics research, and a central component of the activities of GOHaD, is the identification and functional validation of the specific genetic variants that confer susceptibility to disease. The hope is that this molecular knowledge will be translated into new medicines, including diagnostic and prognostic tests that along with new drug treatments can be used to dramatically reduce individual suffering and the enormous health burden to society. These research ou [...]Read More